快速发育生长因子同源蛋白4抗体
规格：1尘驳/1尘濒
英文名： Sprouty 4
别名： Protein sprouty homolog 4; Sprouty homolog 4; sprouty homolog 4 (Drosophila); SPRY 4; Spry-4; Spry4; SPY4_HUMAN.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Sprouty
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse,
细胞定位：细胞浆
快速发育生长因子同源蛋白4抗体产物介绍：background: SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).[supplied by OMIM, Mar 2008] Function: Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the快速发育生长因子同源蛋白4抗体 formation of GTP-Ras. Subcellular Location: Cytoplasm. Cell projection > ruffle membrane. Similarity: Belongs to the sprouty family. Contains 1 SPR (sprouty) domain. Gene ID: 81848 Database links: Entrez Gene: 81848 Human Entrez Gene: 504593 Cow Entrez Gene: 24066 Mouse Omim: 607984 Human SwissProt: A2VDU1 Cow SwissProt: Q9C004 Human SwissProt: Q9WTP2 Mouse Unigene: 323308 快速发育生长因子同源蛋白4抗体Human Unigene: 42038 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
快速发育生长因子同源蛋白4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid