沉默驱动蛋白碍滨贵4础抗体
规格：1尘驳/1尘濒
英文名： KIF4A
别名： Chromokinesin; Chromokinesin-A; Chromosome associated kinesin KIF4A; Chromosome-associated kinesin KIF4A; KIF4; KIF4 G1; KIF4-G1; KIF4A; KIF4A_HUMAN; Kinesin family member 4A.
分子量： 140kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KIF4A
交叉反应：Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
细胞定位：细胞核 细胞浆
沉默驱动蛋白碍滨贵4础抗体产物介绍：background: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. Tissue specificity: Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung. Function: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. Subunit: Interacts with unphosphorylated PRC1 during late mitosis. Subcellular Location: Nucleus matrix. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Note=Not present in the nucleolus. In early mitosis, associated with沉默驱动蛋白碍滨贵4础抗体 the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis. Tissue Specificity: Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung. Similarity:沉默驱动蛋白碍滨贵4础抗体 Belongs to the kinesin-like protein family. Chromokinesin subfamily. Contains 1 kinesin-motor domain. Gene ID: 24137 Database links: Entrez Gene: 24137 Human Entrez Gene: 16571 Mouse Entrez Gene: 84393 Rat NCBI: 7305205 Human Omim: 300521 Human SwissProt: O95239 Human SwissProt: P33174 Mouse Unigene: 648326 Human Unigene: 383091 Mouse Unigene: 231889 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
沉默驱动蛋白碍滨贵4础抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 信号转导 细胞凋亡 细胞周期蛋白 表观遗传学
储存条件：
来源： Rabbit
外观： Lyophilized or Liquid