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凋亡加强结构域蛋白8抗体

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产物名称: 凋亡加强结构域蛋白8抗体
产物型号: CARD8
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

凋亡加强结构域蛋白8抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。凋亡加强结构域蛋白8抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


凋亡加强结构域蛋白8抗体  的详细介绍

凋亡加强结构域蛋白8抗体

规格:1尘驳/1尘濒

英文名: CARD8

别名: Apoptotic protein NDPP 1; Apoptotic protein NDPP1; CARD 8; CARD inhibitor of NF kappa B activating ligand; CARD inhibitor of NF kappaB activating ligand; CARD inhibitor of NF kappaB activating ligands

分子量: 49kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human CARD8

交叉反应:贬耻尘补苍,

细胞定位:细胞核 细胞浆

凋亡加强结构域蛋白8抗体产物介绍:background: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases. Function: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function 凋亡加强结构域蛋白8抗体would be the activation of proinflammatory caspases. [SUBUNIT] May form homodimers. Interacts with NEMO and DRAL. Binds to caspase-1, CARD16/pseudo-ICE and CARD18/ICEBERG. Interacts with FNBP3 (By similarity). Interacts with NALP2 NACHT domain. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: High expression in lung, ovary, testis and placenta. Lower expression in heart, kidney and liver. Also expressed in spleen, lymph node and bone marrow. Similarity: Contains 1 CARD domain. Gene ID: 22900 Database links:凋亡加强结构域蛋白8抗体 Entrez Gene: 22900 Human Omim: 609051 Human SwissProt: Q9Y2G2 Human Unigene: 446146 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

凋亡加强结构域蛋白8抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  细胞凋亡  

储存条件:

来源: Rabbit

外观: Lyophilized or Liquid




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