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卷曲螺旋结构域蛋白50抗体

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产物名称: 卷曲螺旋结构域蛋白50抗体
产物型号: CCDC50
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

卷曲螺旋结构域蛋白50抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。卷曲螺旋结构域蛋白50抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


卷曲螺旋结构域蛋白50抗体  的详细介绍

卷曲螺旋结构域蛋白50抗体

规格:1尘驳/1尘濒

英文名: CCDC50

别名: C3orf6; C3orf6 YMER; CCD50_HUMAN; CCDC 50; Ccdc50; Chromosome 3 open reading frame 6; Coiled coil domain containing 50; Coiled coil domain containing protein 50; Coiled-coil domain-containing protein

分子量: 34kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human CCDC50

交叉反应:Human, Mouse, Rat,

细胞定位:

卷曲螺旋结构域蛋白50抗体产物介绍:background: This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]. Function: Involved in EGFR signaling. Tissue Specificity: Isoform 1 and isoform 2 are co-expressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart. Post-translational modifications: Phosphorylated on tyrosine residues. DISEASE: Defects in CCDC50 are the卷曲螺旋结构域蛋白50抗体 cause of deafness autosomal dominant type 44 (DFNA44) . A form of non-syndromic hearing loss. It is initially moderate and affects mainly low to mid frequencies. Later, it progresses to involve all the frequencies and leads to a profound hearing loss by the 6th decade. The onset of the hearing loss occurs in the first decade of life. Database links: Entrez Gene: 152137 Human Entrez Gene:卷曲螺旋结构域蛋白50抗体 67501 Mouse Entrez Gene: 288022 Rat SwissProt: Q8IVM0 Human SwissProt: Q3TNK7 Mouse SwissProt: Q3TRW1 Mouse SwissProt: Q810U5 Mouse SwissProt: Q810U0 Rat Unigene: 478682 Human Unigene: 258985 Mouse Unigene: 9610 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

卷曲螺旋结构域蛋白50抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  **学  表观遗传学  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid




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