核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体
规格：1尘驳/1尘濒
英文名： Nucleostemin
别名： E2 induced gene 3 protein; E2IG3; Estradiol induced nucleotide binding protein; GNL3; Guanine nucleotide binding protein like 3 (nucleolar); Guanine nucleotide binding protein like 3; MGC800; NNP47; N
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Nucleost
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞核
核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体产物介绍：background: Nucleostemin is a protein found in the nucleoli of embryonic stem cells, CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most tissues. It has been suggested to play a role in controlling the cell cycle progression in stem cells and cancer cells. Function: May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis. Subunit: Interacts with MDM2; this interaction stabilizes MDM2. Interaction with MDM2 occurs in the nucleoplasm and is triggered by a nucleolar release mechanism, such as mitosis-induced nucleolar disassembly (By similarity). Indirectly interacts with TP53, via MDM2-binding (By similarity). Subcellular Location: Nucleus. Nucleus. nucleolus. 核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体Shuttles between the nucleus and nucleolus. Tissue Specificity: Increased levels in lung tissue in cancer patients. Similarity: Belongs to the MMR1/HSR1 GTP-binding protein family. Contains 1 G (guanine nucleotide-binding) domain. Gene ID:核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体 26354 Database links: Entrez Gene: 26354 Human Entrez Gene: 30877 Mouse Entrez Gene: 290556 Rat Omim: 608011 Human SwissProt: Q9BVP2 Human SwissProt: Q8CI11 Mouse SwissProt: Q811S9 Rat Unigene: 313544 Human Unigene: 88512 Mouse Unigene: 4110 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核干细胞因子鸟嘌呤核苷酸结合蛋白3抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 干细胞 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid